Assessing the Next Wave of Oncology First Launches

Posted by Ben Hohn on Jul 2, 2019 11:39:30 AM

Judith Kulich, Jon Roffman, Cody Powers and Renuka Agarwal co-wrote this blog post with Ben Hohn.

The 2019 BIO International Conference, held June 3-6 in Philadelphia, attracted more than 16,000 attendees from more than 70 countries, with representation from biotechnology and pharmaceutical companies, academic institutions, regulators, investors and other organizations. The conference provided a platform for discovery and discussion, resulting in more than 41,000 partnering meetings.


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‘Me Too’ or Breakthrough? Exploring the Oncology Cell Therapy Pipeline

Posted by Katie Blodgett on Jun 26, 2019 8:00:00 AM

Last year, the American Society of Clinical Oncology (ASCO) designated adoptive cell immunotherapy the 2018 clinical cancer “advance of the year” following the 2017 FDA approvals of Kymriah (Novartis) and Yescarta (Kite, a Gilead company). In the year since, we have seen some incremental, notable approvals in the cell and gene therapy space, but we have yet to see additional cell therapy approvals in oncology. However, like a duck sailing smoothly across the water, the relative inactivity above the surface conceals a flurry of development activity taking place below the surface in the oncology pipeline.


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Why Real-World Evidence Is Important for Real-World Cancer Patients

Posted by Jon Roffman on Jun 24, 2019 9:44:47 AM

“A lot of clinical trials are a bit artificial in that the eligibility criteria are ‘purple and pink polka dot patients,’ [but those patients] really don't exist.”

That was the start of my conversation with Dr. Julie Vose at the 2019 American Society of Clinical Oncology (ASCO) annual meeting, where we sat down to talk about real-world evidence and its importance in oncology. Dr. Vose is a believer in evidence-based medicine, and real-world evidence is an important tool in her arsenal for making treatment decisions at the University of Nebraska Medical Center, where she is the head of hematology and oncology.


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The CAR-T First-Mover Advantage: Reality or Myth?

Posted by Sharon Karlsberg on Mar 12, 2019 8:00:00 AM

Robert Rovner co-wrote this blog post with Sharon Karlsberg. This article originally appeared in the January 2019 issue of OBR Green.

The “first-mover advantage” is something we’ve come to expect in the commercial world. The first to innovate and come to market usually reaps the greatest rewards, right? Facebook, Uber and Google improved on technology brought to market by actual first-movers MySpace, Sidecar and AltaVista, but then transcended them by addressing their weaknesses.


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Using the ‘Goldilocks Principle’ to Develop Data-Driven Oncology Account Strategies

Posted by Anshul Agarwal on Jan 15, 2019 8:00:00 AM

Scott Sandford and Abhishek Singh co-wrote this blog post with Anshul Agarwal.

The “Goldilocks principle,” which borrows its concept from the famous children’s story to describe when something is “just right,” can be applied to many situations, and the oncology landscape is no exception. Given the evolution of pharmaceutical manufacturer strategies in approaching oncology accounts and the data needed to support these strategies, manufacturers need to know what’s “just right” when it comes determining the resources needed for each account—a lesson that they can learn from Ms. Goldilocks and her friends, the bears.


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